Monitoring the contents of six steroidal and phenolic endocrine disrupting chemicals in chicken, fish and aquaculture pond water samples using pre-column derivatization and dispersive liquid-liquid microextraction with the aid of experimental design methodology

NWIPB OpenIR

	Monitoring the contents of six steroidal and phenolic endocrine disrupting chemicals in chicken, fish and aquaculture pond water samples using pre-column derivatization and dispersive liquid-liquid microextraction with the aid of experimental design methodology
	Wu, Hongliang ; Li, Guoliang ; Liu, Shucheng ; Hu, Na ; Geng, Dandan ; Chen, Guang ; Sun, Zhiwei ; Zhao, Xianen ; Xia, Lian ; You, Jinmao
	2016-02-01
发表期刊	FOOD CHEMISTRY
摘要	This research established a sensitive and efficient pre-column derivatization HPLC method based on dispersive liquid-liquid microextraction (DLLME) for the simultaneous determination of six steroidal and phenolic endocrine disrupting chemicals (EDCs). In this study, EDCs were firstly labeled by the derivatization reagent 2-(11H-benzo[a]carbazol-11-yl) ethyl carbonochloridate (BCEC-Cl) and then extracted by DLLME. The response surface methodology was employed to investigate the key parameters of pre-column derivatization and DLLME. Under the optimal conditions, a good linear relationship between the peak area and the concentration of analytes was observed with correlation coefficients of >0.9991. Limits of detection for all EDCs derivatives were achieved within the range of 0.02-0.07 mu g L-1. The proposed method has the advantages of simple operation, low consumption of organic solvent, saving time, low output limit and good selectivity. When applied to several food and water samples analysis, it demonstrated good applicability for the determination of EDCs. (C) 2015 Elsevier Ltd. All rights reserved.
文献类型	期刊论文
条目标识符	http://210.75.249.4/handle/363003/48253
专题	中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	Wu, Hongliang,Li, Guoliang,Liu, Shucheng,et al. Monitoring the contents of six steroidal and phenolic endocrine disrupting chemicals in chicken, fish and aquaculture pond water samples using pre-column derivatization and dispersive liquid-liquid microextraction with the aid of experimental design methodology[J]. FOOD CHEMISTRY,2016.
APA	Wu, Hongliang.,Li, Guoliang.,Liu, Shucheng.,Hu, Na.,Geng, Dandan.,...&You, Jinmao.(2016).Monitoring the contents of six steroidal and phenolic endocrine disrupting chemicals in chicken, fish and aquaculture pond water samples using pre-column derivatization and dispersive liquid-liquid microextraction with the aid of experimental design methodology.FOOD CHEMISTRY.
MLA	Wu, Hongliang,et al."Monitoring the contents of six steroidal and phenolic endocrine disrupting chemicals in chicken, fish and aquaculture pond water samples using pre-column derivatization and dispersive liquid-liquid microextraction with the aid of experimental design methodology".FOOD CHEMISTRY (2016).