Knowledge Management System of Northwest Institute of Plateau Biology, CAS
Effectiveness of 10 polymorphic microsatellite markers for parentage and pedigree analysis in plateau pika (Ochotona curzoniae) | |
Li, Kexin ; Geng, Jianing ; Qu, Jiapeng ; Zhang, Yanming ; Hu, Songnian | |
2010-11-10 | |
发表期刊 | BMC GENETICS
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摘要 | Background: The plateau pika (Ochotona curzoniae) is an underground-dwelling mammal, native to the Tibetan plateau of China. A set of 10 polymorphic microsatellite loci has been developed earlier. Its reliability for parentage assignment has been tested in a plateau pika population. Two family groups with a known pedigree were used to validate the power of this set of markers. Results: The error in parentage assignment using a combination of these 10 loci was very low as indicated by their power of discrimination (0.803 - 0.932), power of exclusion (0.351 - 0.887), and an effectiveness of the combined probability of exclusion in parentage assignment of 99.999%. Conclusion: All the offspring of a family could be assigned to their biological mother; and their father or relatives could also be identified. This set of markers therefore provides a powerful and efficient tool for parentage assignment and other population analyses in the plateau pika.; Background: The plateau pika (Ochotona curzoniae) is an underground-dwelling mammal, native to the Tibetan plateau of China. A set of 10 polymorphic microsatellite loci has been developed earlier. Its reliability for parentage assignment has been tested in a plateau pika population. Two family groups with a known pedigree were used to validate the power of this set of markers. |
文献类型 | 期刊论文 |
条目标识符 | http://210.75.249.4/handle/363003/51033 |
专题 | 中国科学院西北高原生物研究所 |
推荐引用方式 GB/T 7714 | Li, Kexin,Geng, Jianing,Qu, Jiapeng,et al. Effectiveness of 10 polymorphic microsatellite markers for parentage and pedigree analysis in plateau pika (Ochotona curzoniae)[J]. BMC GENETICS, Li, KX; Geng, JN; Qu, JP; Zhang, YM; Hu, SN.Effectiveness of 10 polymorphic microsatellite markers for parentage and pedigree analysis in plateau pika (Ochotona curzoniae),BMC GENETICS,2010,11():,2010. |
APA | Li, Kexin,Geng, Jianing,Qu, Jiapeng,Zhang, Yanming,&Hu, Songnian.(2010).Effectiveness of 10 polymorphic microsatellite markers for parentage and pedigree analysis in plateau pika (Ochotona curzoniae).BMC GENETICS. |
MLA | Li, Kexin,et al."Effectiveness of 10 polymorphic microsatellite markers for parentage and pedigree analysis in plateau pika (Ochotona curzoniae)".BMC GENETICS (2010). |
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