NWIPB OpenIR
Adaptive Evolution of the Eda Gene and Scales Loss in Schizothoracine Fishes in Response to Uplift of the Tibetan Plateau
Zhang, Cunfang; Tong, Chao; Ludwig, Arne; Tang, Yongtao; Liu, Sijia; Zhang, Renyi; Feng, Chenguang; Li, Guogang; Peng, Zuogang; Zhao, Kai
2018
发表期刊INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
卷号19期号:10
摘要Schizothoracine is the predominant wild fish subfamily of the Tibetan plateau (TP). Their scales, pharyngeal teeth and barbels have gradually regressed with increasing altitude. Schizothoracine have been divided into three groups: primitive, specialized and highly specialized. Ectodysplasin-A (Eda) has been considered as a major gene that contributes to the development of skin appendages. The present study cloned the Eda genes of 51 Schizothoracine fish species which represent the three groups and five Barbinae species. Phylogenetic analyses indicated that Eda may have acted as the genetic trigger for scale loss in the Schizothoracine. Furthermore, 14 single nucleotide polymorphisms (SNPs) and two deletions (18 bp and 6 bp in size), were also detected in the Eda coding sequence of the highly specialized group compared to the primitive group. The same SNPs and two indels result in four non-synonymous and two G-X-Y and 1 XY motif indels, which possibly contribute to significant structure changes in the Eda gene. The domain including (G-X-Y)(n) motif in the Eda gene is relatively conserved amongst teleosts. Based on the above results, we hypothesize that the evolution of Eda gene might be associated with the scale loss in Schizothoracine fishes in response to the phased uplift of the TP.
关键词Tibetan plateau Schizothoracine scale loss Eda gene adaptive evolution
文献类型期刊论文
条目标识符http://210.75.249.4/handle/363003/59963
专题中国科学院西北高原生物研究所
推荐引用方式
GB/T 7714
Zhang, Cunfang,Tong, Chao,Ludwig, Arne,et al. Adaptive Evolution of the Eda Gene and Scales Loss in Schizothoracine Fishes in Response to Uplift of the Tibetan Plateau[J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2018,19(10).
APA Zhang, Cunfang.,Tong, Chao.,Ludwig, Arne.,Tang, Yongtao.,Liu, Sijia.,...&Zhao, Kai.(2018).Adaptive Evolution of the Eda Gene and Scales Loss in Schizothoracine Fishes in Response to Uplift of the Tibetan Plateau.INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,19(10).
MLA Zhang, Cunfang,et al."Adaptive Evolution of the Eda Gene and Scales Loss in Schizothoracine Fishes in Response to Uplift of the Tibetan Plateau".INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 19.10(2018).
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Zhang, Cunfang]的文章
[Tong, Chao]的文章
[Ludwig, Arne]的文章
百度学术
百度学术中相似的文章
[Zhang, Cunfang]的文章
[Tong, Chao]的文章
[Ludwig, Arne]的文章
必应学术
必应学术中相似的文章
[Zhang, Cunfang]的文章
[Tong, Chao]的文章
[Ludwig, Arne]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。