Enzyme-Mimetic nano-immunosensors for amplified detection of food hazards: Recent advances and future trends

NWIPB OpenIR

	Enzyme-Mimetic nano-immunosensors for amplified detection of food hazards: Recent advances and future trends
	Shu, R; Liu, SJ; Huang, LJ; Li, YC; Sun, J; Zhang, DH; Zhu, MQ; Wang, JL
	2022
发表期刊	BIOSENSORS & BIOELECTRONICS
卷号	217
摘要	The grave threat posed by food hazards to food security and human health has increased the urgency of rapid and sensitive detection. Enzyme-mimic immune detection, particularly nanozyme-activated food immunosensors (NAFI), shows distinct specificity and catalytic properties, advancing food safety supervision. However, knowledge of the fundamental principles and functionalities of NAFI is still limited. Based on tracking the timeline of the independent evolution and combination of immunosensors and nanozymes, we first provide a systemic view to describe the trends of NAFI. Moreover, the underlying catalytic mechanisms are discussed according to classification in this review, including metal-based, carbon-based, and metal-organic framework -based nanozymes. In particular, significant attention is focused on the fundamental function of nanozyme re-ceptors in food immunosensors, including the connection between nanozymes and bio-affinity ligands (one pot and two steps), signal modulation and amplification, and various signal outputs (typical and novel modes), which are crucial for gaining the best performance and further innovation. Finally, based on representative applications of nanozymes to detect food hazards, the main challenges in the development of NAFI are summarized, and future research directions for this highly prospective frontier are envisioned.
收录类别	SCIE
文献类型	期刊论文
条目标识符	http://210.75.249.4/handle/363003/61048
专题	中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	Shu, R,Liu, SJ,Huang, LJ,et al. Enzyme-Mimetic nano-immunosensors for amplified detection of food hazards: Recent advances and future trends[J]. BIOSENSORS & BIOELECTRONICS,2022,217.
APA	Shu, R.,Liu, SJ.,Huang, LJ.,Li, YC.,Sun, J.,...&Wang, JL.(2022).Enzyme-Mimetic nano-immunosensors for amplified detection of food hazards: Recent advances and future trends.BIOSENSORS & BIOELECTRONICS,217.
MLA	Shu, R,et al."Enzyme-Mimetic nano-immunosensors for amplified detection of food hazards: Recent advances and future trends".BIOSENSORS & BIOELECTRONICS 217(2022).