Knowledge Management System of Northwest Institute of Plateau Biology, CAS
A one-pot synthesis of PEGylated plasmonic WO3-x@Eugenol nanoflowers with NIR-controllable antioxidant activities for synergetically combating bacterial biofilm infection | |
Xie, XH; Zhang, MY; Lei, YL; Li, Y![]() | |
2022 | |
发表期刊 | INORGANIC CHEMISTRY FRONTIERS
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卷号 | 9期号:15页码:3808 |
摘要 | Serious wound infection by the colonization and development of drug-resistant bacteria has attracted widespread attention of the society with the urge for searching advanced antibacterial methods. The NIR-triggered antimicrobial photothermal therapy (PTT) using nanomaterials as energy donors has the advantage of a wide antibacterial spectrum, but it is still restricted by its low efficacy. Herein, we propose a PTT-driven bioactive molecule controllable release system (PEG-WO3-x@EL NFs), which is developed with tungsten trioxide nanoflowers as a carrier. Benefiting from the photothermal effect of PEG-WO3-x NFs and the inherent bactericidal properties of EL (eugenol), the nanoplatform achieves an extremely strong bactericidal ability against Salmonella and methicillin-resistant Staphylococcus aureus. Notably, the nanoplatform presents outstanding capacity to prevent biofilm formation. More importantly, the nanoplatform displays significant antioxidant capacity to realize the rapid recovery of infected wounds. As a consequence, our study has the potential to provide an urgent breakthrough for wound biofilm therapy. |
收录类别 | SCIE |
文献类型 | 期刊论文 |
条目标识符 | http://210.75.249.4/handle/363003/61184 |
专题 | 中国科学院西北高原生物研究所 |
推荐引用方式 GB/T 7714 | Xie, XH,Zhang, MY,Lei, YL,et al. A one-pot synthesis of PEGylated plasmonic WO3-x@Eugenol nanoflowers with NIR-controllable antioxidant activities for synergetically combating bacterial biofilm infection[J]. INORGANIC CHEMISTRY FRONTIERS,2022,9(15):3808. |
APA | Xie, XH.,Zhang, MY.,Lei, YL.,Li, Y.,Sun, J.,...&Wang, JL.(2022).A one-pot synthesis of PEGylated plasmonic WO3-x@Eugenol nanoflowers with NIR-controllable antioxidant activities for synergetically combating bacterial biofilm infection.INORGANIC CHEMISTRY FRONTIERS,9(15),3808. |
MLA | Xie, XH,et al."A one-pot synthesis of PEGylated plasmonic WO3-x@Eugenol nanoflowers with NIR-controllable antioxidant activities for synergetically combating bacterial biofilm infection".INORGANIC CHEMISTRY FRONTIERS 9.15(2022):3808. |
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