A one-pot synthesis of PEGylated plasmonic WO3-x@Eugenol nanoflowers with NIR-controllable antioxidant activities for synergetically combating bacterial biofilm infection

NWIPB OpenIR

	A one-pot synthesis of PEGylated plasmonic WO3-x@Eugenol nanoflowers with NIR-controllable antioxidant activities for synergetically combating bacterial biofilm infection
	Xie, XH; Zhang, MY; Lei, YL; Li, Y; Sun, J; Sattorov, N; Makhmudov, KB; Zhu, MQ; Wang, JL
	2022
发表期刊	INORGANIC CHEMISTRY FRONTIERS
卷号	9 期号:15 页码:3808
摘要	Serious wound infection by the colonization and development of drug-resistant bacteria has attracted widespread attention of the society with the urge for searching advanced antibacterial methods. The NIR-triggered antimicrobial photothermal therapy (PTT) using nanomaterials as energy donors has the advantage of a wide antibacterial spectrum, but it is still restricted by its low efficacy. Herein, we propose a PTT-driven bioactive molecule controllable release system (PEG-WO3-x@EL NFs), which is developed with tungsten trioxide nanoflowers as a carrier. Benefiting from the photothermal effect of PEG-WO3-x NFs and the inherent bactericidal properties of EL (eugenol), the nanoplatform achieves an extremely strong bactericidal ability against Salmonella and methicillin-resistant Staphylococcus aureus. Notably, the nanoplatform presents outstanding capacity to prevent biofilm formation. More importantly, the nanoplatform displays significant antioxidant capacity to realize the rapid recovery of infected wounds. As a consequence, our study has the potential to provide an urgent breakthrough for wound biofilm therapy.
收录类别	SCIE
文献类型	期刊论文
条目标识符	http://210.75.249.4/handle/363003/61184
专题	中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	Xie, XH,Zhang, MY,Lei, YL,et al. A one-pot synthesis of PEGylated plasmonic WO3-x@Eugenol nanoflowers with NIR-controllable antioxidant activities for synergetically combating bacterial biofilm infection[J]. INORGANIC CHEMISTRY FRONTIERS,2022,9(15):3808.
APA	Xie, XH.,Zhang, MY.,Lei, YL.,Li, Y.,Sun, J.,...&Wang, JL.(2022).A one-pot synthesis of PEGylated plasmonic WO3-x@Eugenol nanoflowers with NIR-controllable antioxidant activities for synergetically combating bacterial biofilm infection.INORGANIC CHEMISTRY FRONTIERS,9(15),3808.
MLA	Xie, XH,et al."A one-pot synthesis of PEGylated plasmonic WO3-x@Eugenol nanoflowers with NIR-controllable antioxidant activities for synergetically combating bacterial biofilm infection".INORGANIC CHEMISTRY FRONTIERS 9.15(2022):3808.