Knowledge Management System of Northwest Institute of Plateau Biology, CAS
Obtaining alantolactone and isoalantolactone from Inula racemose Hook.f. by optimized supercritical fluid extraction | |
Chi, Xiao-Feng1,2,3; Yue, Hui-Lan1; Zhao, Xiao-Hui1,2; Hu, Feng-Zu1 | |
2016 | |
发表期刊 | INDUSTRIAL CROPS AND PRODUCTS |
卷号 | 79页码:63-69 |
文章类型 | Article |
摘要 | Inula racemose Hook.f. (I. racemosa) is a traditional herbal medicine with strong anti-fungal and anti-inflammation activity while alantolactone (AL) and isoalantolactone (IAL) are the major active compounds of this plant. The aim of this paper was obtaining AL and IAL from the radix off. racemosa by supercritical fluid extraction (SFE) which was optimized by response surface methodology (RSM). Our results showed that, the optimal conditions for maximum extraction efficiency were as follows: pressure 20 MPa, extraction temperature 50 degrees C, carbon dioxide (CO2) flow rate of 17.0 x 10(-5) kg/s and extraction time of 40 min. Subsequently, an efficient freezing method was developed for purification of AL and IAL in the crude extract obtained from SFE. After purification by freezing, the total content of the target compounds was greatly improved by 30.7%. The results demonstrate that SFE coupled with freezing would be a powerful technique for extraction and purification of AL and IAL from the radix off. racemosa. (C) 2015 Elsevier B.V. All rights reserved. |
关键词 | Inula Racemose Hook.f Alantolactone Isoalantolactone Supercritical Fluid Extraction Response Surface Methodology Freezing |
WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
DOI | 10.1016/j.indcrop.2015.10.025 |
关键词[WOS] | SUBCRITICAL WATER EXTRACTION ; SESQUITERPENE LACTONES ; LIQUID-CHROMATOGRAPHY ; ESSENTIAL OIL ; HELENIUM ; EUDESMANOLIDES |
收录类别 | SCI |
语种 | 英语 |
项目资助者 | National Natural Science Foundation of China(21202196) ; Application Basic Research of QingHai Science and Technology Department(2015-ZJ-726) ; West Light Foundation of the Chinese Academy of Sciences ; Basic Research of Huzhou Science and Technology Department(2012GN27) |
WOS研究方向 | Agriculture |
WOS类目 | Agricultural Engineering ; Agronomy |
WOS记录号 | WOS:000367857300008 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://210.75.249.4/handle/363003/6501 |
专题 | 中国科学院西北高原生物研究所 |
作者单位 | 1.Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Tibetan Med Res, Xining 810008, Peoples R China 2.Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Adaptat & Evolut Plateau Biota, Xining 810008, Peoples R China 3.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China |
推荐引用方式 GB/T 7714 | Chi, Xiao-Feng,Yue, Hui-Lan,Zhao, Xiao-Hui,et al. Obtaining alantolactone and isoalantolactone from Inula racemose Hook.f. by optimized supercritical fluid extraction[J]. INDUSTRIAL CROPS AND PRODUCTS,2016,79:63-69. |
APA | Chi, Xiao-Feng,Yue, Hui-Lan,Zhao, Xiao-Hui,&Hu, Feng-Zu.(2016).Obtaining alantolactone and isoalantolactone from Inula racemose Hook.f. by optimized supercritical fluid extraction.INDUSTRIAL CROPS AND PRODUCTS,79,63-69. |
MLA | Chi, Xiao-Feng,et al."Obtaining alantolactone and isoalantolactone from Inula racemose Hook.f. by optimized supercritical fluid extraction".INDUSTRIAL CROPS AND PRODUCTS 79(2016):63-69. |
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