Norlathyrane Diterpenes from the Root of Euphorbia kansuensis

doi:10.1002/cbdv.201300004

NWIPB OpenIR

	Norlathyrane Diterpenes from the Root of Euphorbia kansuensis
	Zhang, Bei-Bei 1; Jiang, Qian 1; Liao, Zhi-Xin 1; Liu, Chao 1; Liu, Shi-Jun 1; Ji, Lan-Ju 2; Sun, Hong-Fa 2
	2013-10-01
发表期刊	CHEMISTRY & BIODIVERSITY
卷号	10 期号:10 页码:1887-1893
文章类型	Article
摘要	Phytochemical investigation of the EtOH extract obtained from the root of the Euphorbia kansuensisProch. grown in China resulted in the isolation of two novel norlathyrane diterpenes, named ekanpenoids A and B (1 and 2, resp.). Their structures were established by extensive 1D- and 2D-NMR spectroscopy, as well as other spectra. The isolated diterpenes exhibited potent cytotoxic activities against the HeLa and Hep-G2 cell lines with the IC50 values ranging from 3.6 to 9.7 mu g/ml.
关键词	Euphorbia Kansuensis Diterpenes Norlathyrane Cytotoxic Activity Ekanpenoids a And b
WOS标题词	Science & Technology ; Life Sciences & Biomedicine ; Physical Sciences
DOI	10.1002/cbdv.201300004
关键词[WOS]	MACROCYCLIC LATHYRANE DITERPENES ; CELLS
收录类别	SCI
语种	英语
项目资助者	National Natural Science Foundation of China(30770233) ; State Key Laboratory Cultivation Base for the Chemistry and Molecular Engineering of Medicinal Resources, Ministry of Science and Technology of China(CMEMR2012-B09) ; Foundation of the Research and Innovation Project for College Graduates of Jiangsu Province(CXZZ_0173)
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry
WOS类目	Biochemistry & Molecular Biology ; Chemistry, Multidisciplinary
WOS记录号	WOS:000328134400012
引用统计	被引频次：9[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://210.75.249.4/handle/363003/6680
专题	中国科学院西北高原生物研究所
作者单位	1.Southeast Univ, Sch Chem & Chem Engn, Dept Pharmaceut Engn, Nanjing 211189, Jiangsu, Peoples R China 2.Chinese Acad Sci, Northweast Inst Plateau Biol, Xining 810008, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Bei-Bei,Jiang, Qian,Liao, Zhi-Xin,et al. Norlathyrane Diterpenes from the Root of Euphorbia kansuensis[J]. CHEMISTRY & BIODIVERSITY,2013,10(10):1887-1893.
APA	Zhang, Bei-Bei.,Jiang, Qian.,Liao, Zhi-Xin.,Liu, Chao.,Liu, Shi-Jun.,...&Sun, Hong-Fa.(2013).Norlathyrane Diterpenes from the Root of Euphorbia kansuensis.CHEMISTRY & BIODIVERSITY,10(10),1887-1893.
MLA	Zhang, Bei-Bei,et al."Norlathyrane Diterpenes from the Root of Euphorbia kansuensis".CHEMISTRY & BIODIVERSITY 10.10(2013):1887-1893.