Alkaloids and phenolics identification in fruit of Nitraria tangutorum Bobr. by UPLC-Q-TOF-MS/MS and their a-glucosidase inhibitory effects in vivo and in vitro

NWIPB OpenIR

	Alkaloids and phenolics identification in fruit of Nitraria tangutorum Bobr. by UPLC-Q-TOF-MS/MS and their a-glucosidase inhibitory effects in vivo and in vitro
	Jiang, Sirong; Chen, Chen; Dong, Qi; Shao, Yun; Zhao, Xiaohui; Tao, Yanduo; Yue, Huilan
	2021
发表期刊	FOOD CHEMISTRY
卷号	364
摘要	Nitraria tangutorum Bobr. (NTB), mainly distributed in the Qaidam Basin of Tibetan Plateau, have high economic, ecological and medicinal value. The chemical compositions in the NTB fruits were tentatively analyzed and characterized by applying UPLC-Q-TOF-MS/MS. Total 45 constituents, including 9 hydroxycinnamic acids derivatives, 12 flavonols, 4 flavonoids, 1 trolox derivative, 8 beta-carboline alkaloids, 4 tryptophan derivatives, and 7 other amino acid derivatives were identified by comparing with standard products, and analyzing their retention times, characteristic fragment ions and deprotonated molecule ions. The activity studies in vitro indicated that NTB-Z and NTB-C extracts had marked inhibitory effects against sucrase and maltase. Further sucrose/maltose/starch tolerance experiment demonstrated that both NTB-Z and NTB-C extracts at 400 mg/kg could markedly lower the postprandial blood glucose (PBG) level in diabetic animals. All these results indicated that the NTB fruits could be used as the functional health food or medicine for controlling postprandial blood glucose level.
关键词	Nitraria tangutorum Bobr flavonoids Phenolic acids Alkaloids Postprandial blood glucose Sucrose Maltase
文献类型	期刊论文
条目标识符	http://210.75.249.4/handle/363003/60669
专题	中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	Jiang, Sirong,Chen, Chen,Dong, Qi,et al. Alkaloids and phenolics identification in fruit of Nitraria tangutorum Bobr. by UPLC-Q-TOF-MS/MS and their a-glucosidase inhibitory effects in vivo and in vitro[J]. FOOD CHEMISTRY,2021,364.
APA	Jiang, Sirong.,Chen, Chen.,Dong, Qi.,Shao, Yun.,Zhao, Xiaohui.,...&Yue, Huilan.(2021).Alkaloids and phenolics identification in fruit of Nitraria tangutorum Bobr. by UPLC-Q-TOF-MS/MS and their a-glucosidase inhibitory effects in vivo and in vitro.FOOD CHEMISTRY,364.
MLA	Jiang, Sirong,et al."Alkaloids and phenolics identification in fruit of Nitraria tangutorum Bobr. by UPLC-Q-TOF-MS/MS and their a-glucosidase inhibitory effects in vivo and in vitro".FOOD CHEMISTRY 364(2021).