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Rapid qualitative and quantitative analyses of eighteen phenolic compounds from Lycium ruthenicum Murray by UPLC-Q-Orbitrap MS and their antioxidant activity
Zhang, Gong1,2,4,5; Chen, Shasha1,4,5; Zhou, Wu1,3,4,5; Meng, Jing1,4,5; Deng, Kai1,4,5; Zhou, Haonan1,4,5; Hu, Na1,4; Suo, Yourui1,3,4
2018-12-15
Source PublicationFOOD CHEMISTRY
ISSN0308-8146
Volume269Pages:150-156
SubtypeArticle
AbstractLycium ruthenicum Murray (LR) is a functional food, and it has long been used in traditional folk medicine. However, detailed qualitative and quantitative analyses related to its phenolic compounds remains scarce. This work reports, for the first time, the establishment of a rapid method for simultaneous identification and quantification of 25 phenolic compounds by UPLC-quadrupole-Orbitrap mass spectrometry (UPLC-Q-Orbitrap MS). This method was validated by LODs, LOQs, precision, repeatability, stability, mean recovery, recovery range and RSD. The confirmed method was applied to the analysis of phenolic compounds in LR. Finally, 18 phenolic compounds in LR were qualitatively and quantitatively analyzed. Among them, 11 constituents were detected for the first time, which included two flavonoids (catechin and naringenin) and seven phenolic acids (gallic acid, vanillic acid, 2,4-dihydroxybenzoic acid, veratronic acid, benzoic acid, ellagic acid and salicylic acid). Moreover, Phloretin and protocatechuate, belonging to the dihydrochalcone flavonoid and protocatechuic acid respectively, were also identified and quantified. The total phenolics content (20.17 +/- 2.82 mg/g) and the total anthocyanin content (147.43 +/- 1.81 mg/g) were determined. In addition, the antioxidant activities of the LR extract were evaluated through 2,2-azinobis (3-ethylbenzthiazoline-6-sulphonic acid) (ABTS) radical scavenging activity, ferric reducing antioxidant power (FRAP) and total antioxidant activity (T-AOC) assays.
KeywordLycium Ruthenicum Murray Orbitrap Ms Phenolic Compounds Antioxidant
WOS HeadingsScience & Technology ; Physical Sciences ; Life Sciences & Biomedicine
DOI10.1016/j.foodchem.2018.06.132
WOS KeywordSIGNALING PATHWAY ; OXIDATIVE STRESS ; CHLOROGENIC ACID ; INFLAMMATION ; FLAVONOIDS ; RUTIN ; NARINGENIN ; PHLORETIN ; QUERCETIN ; GROWTH
Indexed BySCI
Language英语
Funding OrganizationQinghai Provincial Science Foundation(2016-ZJ-928Q ; CAS, China "Light of West China" Program (2016): Study on the effect of Lycium ruthenicum Murr. anthocyanin on the liver protection, Capacity Building Project of Engineering Research Center of Qinghai Province(2017-GX-G03) ; Innovation Platform for the Development and Construction of Special Project of Key Laboratory of Tibetan Medicine Research of Qinghai Province(2017-ZJ-Y11) ; 2015-NK-509 ; 2015-SF-120)
WOS Research AreaChemistry ; Food Science & Technology ; Nutrition & Dietetics
WOS SubjectChemistry, Applied ; Food Science & Technology ; Nutrition & Dietetics
WOS IDWOS:000441142100019
PublisherELSEVIER SCI LTD
Citation statistics
Cited Times:8[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://210.75.249.4/handle/363003/13781
Collection中国科学院西北高原生物研究所
Corresponding AuthorHu, Na; Suo, Yourui
Affiliation1.Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Tibetan Med Res, Xining 810008, Qinghai, Peoples R China
2.Yanan Univ, Affiliated Hosp, Yanan 716000, Shaanxi, Peoples R China
3.Qinghai Univ, State Key Lab Plateau Ecol & Agr, Xining 810016, Qinghai, Peoples R China
4.Qinghai Prov Key Lab Tibetan Med Res, Xining 810001, Qinghai, Peoples R China
5.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
Recommended Citation
GB/T 7714
Zhang, Gong,Chen, Shasha,Zhou, Wu,et al. Rapid qualitative and quantitative analyses of eighteen phenolic compounds from Lycium ruthenicum Murray by UPLC-Q-Orbitrap MS and their antioxidant activity[J]. FOOD CHEMISTRY,2018,269:150-156.
APA Zhang, Gong.,Chen, Shasha.,Zhou, Wu.,Meng, Jing.,Deng, Kai.,...&Suo, Yourui.(2018).Rapid qualitative and quantitative analyses of eighteen phenolic compounds from Lycium ruthenicum Murray by UPLC-Q-Orbitrap MS and their antioxidant activity.FOOD CHEMISTRY,269,150-156.
MLA Zhang, Gong,et al."Rapid qualitative and quantitative analyses of eighteen phenolic compounds from Lycium ruthenicum Murray by UPLC-Q-Orbitrap MS and their antioxidant activity".FOOD CHEMISTRY 269(2018):150-156.
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