Knowledge Management System of Northwest Institute of Plateau Biology, CAS
Characterization, antioxidant, and neuroprotective effects of anthocyanins from Nitraria tangutorum Bobr. fruit | |
Chen, Shasha; Zhou, Haonan; Zhang, Gong; Dong, Qi; Wang, Zhenhua; Wang, Honglun; Hu, Na | |
2021 | |
发表期刊 | FOOD CHEMISTRY |
卷号 | 353 |
摘要 | An anthocyanin-rich extract was obtained from Nitraria tangutorum Bobr. fruit, namely ANF, and its composition, antioxidant and neuroprotective effects were studied. Nine anthocyanins were identified from the ANF using UPLC-Triple-TOF/MS analysis, and cyanidin-3-[2 ''-(6 '''-coumaroyl)-glucosyl]-glucoside (C3G) is the most abundant anthocyanin (87.06%). ANF exhibited high ferric reducing antioxidant power (FRAP) and ABTS radical scavenging activity. The online HPLC-DPPH screening revealed that C3G contributed the highest antioxidant capacity. ANF showed potential neuroprotective effects by relieving D-Galactose-induced memory deficits, reducing overexpression of receptor for advanced glycation end products (RAGE) and amyloid-beta42 (A beta 42) in the hippocampus of rats. Besides, ANF could inhibit oxidative stress by reducing the levels of reactive oxygen species (ROS) and malondialdehyde (MDA) in the hippocampus, while elevating amounts of total superoxide dismutase (T-SOD) and glutathione (GSH) in the serum of rats. Thus, ANF has great potential in the development of food and health products related to antioxidant and neuroprotective effects. |
关键词 | Nitraria tangutorum Bobr Anthocyanin Composition Antioxidant Neuroprotective effects |
文献类型 | 期刊论文 |
条目标识符 | http://210.75.249.4/handle/363003/60744 |
专题 | 中国科学院西北高原生物研究所 |
推荐引用方式 GB/T 7714 | Chen, Shasha,Zhou, Haonan,Zhang, Gong,et al. Characterization, antioxidant, and neuroprotective effects of anthocyanins from Nitraria tangutorum Bobr. fruit[J]. FOOD CHEMISTRY,2021,353. |
APA | Chen, Shasha.,Zhou, Haonan.,Zhang, Gong.,Dong, Qi.,Wang, Zhenhua.,...&Hu, Na.(2021).Characterization, antioxidant, and neuroprotective effects of anthocyanins from Nitraria tangutorum Bobr. fruit.FOOD CHEMISTRY,353. |
MLA | Chen, Shasha,et al."Characterization, antioxidant, and neuroprotective effects of anthocyanins from Nitraria tangutorum Bobr. fruit".FOOD CHEMISTRY 353(2021). |
条目包含的文件 | 条目无相关文件。 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论