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Porcine enterocyte protein Btnl5 negatively regulates NF-kappa B pathway by interfering p65 nuclear translocation 期刊论文
GENE, 2018, 卷号: 646, 页码: 47-55
作者:  Bao, Qi;  Li, Chong;  Xu, Chongfeng;  Zhang, Ruiying;  Zhao, Kai;  Duan, Ziyuan
收藏  |  浏览/下载：146/0  |  提交时间：2018/07/25
Btnl5  Iecs  Nf-kappa b  Immune Regulation  Interacting Proteins  
Novel Diketopiperazine Dihydroorotate Dehydrogenase Inhibitors Purified from Traditional Tibetan Animal Medicine Osteon Myospalacem Baileyi 期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2015, 卷号: 86, 期号: 4, 页码: 626-636
作者:  Jiang, Lei;  Wen, Huaixiu;  Shao, Yun;  Yu, Ruitao;  Liu, Zenggen;  Wang, Shuo;  Wang, Qilan;  Zhao, Xiaohui;  Zhang, Peng;  Tao, Yanduo;  Mei, Lijuan
浏览  |  Adobe PDF(1151Kb)  |  收藏  |  浏览/下载：359/133  |  提交时间：2015/12/17
Cyclic Dipeptides  Dihydroorotate Dehydrogenase Inhibitors  Osteon Myospalacem Baileyi  Tibetan Medicine  Two-dimensional Chromatography  
Computational Study of Drugs by Integrating Omics Data with Kernel Methods 期刊论文
MOLECULAR INFORMATICS, 2013, 卷号: 32, 期号: 11-12, 页码: 930-941
作者:  Wang, Yongcui C.;  Deng, Naiyang;  Chen, Shilong;  Wang, Yong;  Wang, YCC (reprint author), Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Adaptat & Evolut Plateau Biota, 23 Xinning Rd, Xining, Qinghai Provinc, Peoples R China.
Adobe PDF(1222Kb)  |  收藏  |  浏览/下载：621/154  |  提交时间：2014/05/09
Omics Data  Kernel Methods  Data Integration  Drug-targets  Atc-codes Of Drugs  Drug Repositioning  
Drug Repositioning by Kernel-Based Integration of Molecular Structure, Molecular Activity, and Phenotype Data 期刊论文
PLOS ONE, 2013, 卷号: 8, 期号: 11
作者:  Wang, Yongcui;  Chen, Shilong;  Deng, Naiyang;  Wang, Yong;  Wang, Y (reprint author), Chinese Acad Sci, Acad Math & Syst Sci, Natl Ctr Math & Interdisciplinary Sci, Beijing, Peoples R China.
Adobe PDF(1969Kb)  |  收藏  |  浏览/下载：427/81  |  提交时间：2014/05/09
Network predicting drug's anatomical therapeutic chemical code 期刊论文
BIOINFORMATICS, 2013, 卷号: 29, 期号: 10, 页码: 1317-1324
作者:  Wang, Yong-Cui;  Chen, Shi-Long;  Deng, Nai-Yang;  Wang, Yong;  Wang, Y (reprint author), Chinese Acad Sci, Natl Ctr Math & Interdisciplinary Sci, Beijing 100190, Peoples R China.
Adobe PDF(389Kb)  |  收藏  |  浏览/下载：493/78  |  提交时间：2014/05/09
Kernel-based data fusion improves the drug-protein interaction prediction 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2011, 卷号: 35, 期号: 6, 页码: 353-362
作者:  Wang, Yong-Cui;  Zhang, Chun-Hua;  Deng, Nai-Yang;  Wang, Yong
收藏  |  浏览/下载：129/0  |  提交时间：2017/06/30
Drug-target Interaction  Chemical Space  Pharmacological Space  Therapeutic Space  Genomic Space  Kernel Function  Support Vector Machine  
QM/MM studies on the glycosylation mechanism of rice BGlu1 beta-glucosidase 期刊论文
JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2011, 卷号: 30, 期号: 14, 页码: 148-152
作者:  Wang, Jinhu;  Hou, Qianqian;  Dong, Lihua;  Liu, Yongjun;  Liu, Chengbu
浏览  |  Adobe PDF(420Kb)  |  收藏  |  浏览/下载：1128/278  |  提交时间：2011/12/14
Glycosylation  Beta-glucosidases  Qm/mm  Laminaribiose  Mechanism  
Support vector machine prediction of enzyme function with conjoint triad feature and hierarchical context 期刊论文
BMC SYSTEMS BIOLOGY, 2011, 卷号: 5, 页码: 1-11
作者:  Wang, Yong-Cui;  Wang, Yong;  Yang, Zhi-Xia;  Deng, Nai-Yang
浏览  |  Adobe PDF(544Kb)  |  收藏  |  浏览/下载：638/149  |  提交时间：2011/12/14
Functional Evolution of Leptin of Ochotona curzoniae in Adaptive Thermogenesis Driven by Cold Environmental Stress 期刊论文
PLOS ONE, 2011, 卷号: 6, 期号: 6
作者:  Yang, Jie;  Bromage, Timothy G.;  Zhao, Qian;  Xu, Bao Hong;  Gao, Wei Li;  Tian, Hui Fang;  Tang, Hui Jun;  Liu, Dian Wu;  Zhao, Xin Quan
浏览  |  Adobe PDF(615Kb)  |  收藏  |  浏览/下载：941/185  |  提交时间：2011/12/13
Receptor-based QSAR study for a series of 3,3-disubstituted-5-aryl oxindoles and 6-aryl benzimidazol-2-ones derivatives as progesterone receptor inhibitors 期刊论文
SAR AND QSAR IN ENVIRONMENTAL RESEARCH, 2011, 卷号: 22, 期号: 7-8, 页码: 775-799
作者:  Wang, J. H.;  Hou, Q. Q.;  Tang, K.;  Cheng, X. L.;  Dong, L. H.;  Liu, Y. J.;  Liu, C. B.
浏览  |  Adobe PDF(1310Kb)  |  收藏  |  浏览/下载：1217/270  |  提交时间：2011/12/14
Progesterone Receptor  Comparative Molecular Field Analysis (Comfa)  Comparative Molecular Similarity Indices Analysis (Comsia)  Inhibitor  Qsar