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Probing glutathione reductase activity with graphene quantum dots and gold nanoparticles system 期刊论文
SENSORS AND ACTUATORS B-CHEMICAL, 2018, 卷号: 263, 页码: 27-35
作者:  Yan, Xiaolu;  Zhao, Xian-En;  Sun, Jing;  Zhu, Shuyun;  Lei, Cuihua;  Li, Ru;  Gong, Peiwei;  Ling, Baoping;  Wang, Renjun;  Wang, Hua
收藏  |  浏览/下载:163/0  |  提交时间:2018/07/25
Graphene Quantum Dots  Gold Nanoparticles  Enzyme Catalysis  Glutathione Reductase  Inhibitor Screening  
Fluorimetric evaluation of glutathione reductase activity and its inhibitors using carbon quantum dots 期刊论文
TALANTA, 2016, 卷号: 161, 页码: 769-774
作者:  Zhu, Shuyun;  He, Lei;  Zhang, Fang;  Li, Mengyuan;  Jiao, Shulin;  Li, Yan;  Chen, Mengyuan;  Zhao, Xian-En;  Wang, Hua
收藏  |  浏览/下载:210/0  |  提交时间:2017/02/15
Carbon Quantum Dots  Fluorimetric Assay  Glutathione Reductase  Catalysis Activity  Inhibitor Screening  
DW10075, a novel selective and small-molecule inhibitor of VEGFR, exhibits antitumor activities both in vitro and in vivo 期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 3, 页码: 398-407
作者:  Li, Meng-yuan;  Lv, Yong-cong;  Tong, Lin-jiang;  Peng, Ting;  Qu, Rong;  Zhang, Tao;  Sun, Yi-ming;  Chen, Yi;  Wei, Li-xin;  Geng, Mei-yu;  Duan, Wen-hu;  Xie, Hua;  Ding, Jian
收藏  |  浏览/下载:186/0  |  提交时间:2016/07/19
Dw10075  Vegf/vegf Receptor Inhibitor  Antitumor  Angiogenesis  U87-mg Human Glioblastoma  
Design, synthesis and biological evaluation of O-linked indoles as VEGFR-2 kinase inhibitors (I) 期刊论文
CHINESE CHEMICAL LETTERS, 2015, 卷号: 26, 期号: 9, 页码: 1165-1168
作者:  Gao, Guo-Rui;  Li, Meng-Yuan;  Tong, Lin-Jiang;  Wei, Li-Xin;  Ding, Jian;  Xie, Hua;  Duan, Wen-Hu
浏览  |  Adobe PDF(484Kb)  |  收藏  |  浏览/下载:262/64  |  提交时间:2015/12/17
Vegfr-2  Inhibitor  Indole  
Inhibitory effects of sea buckthorn procyanidins on fatty acid synthase and MDA-MB-231 cells 期刊论文
TUMOR BIOLOGY, 2014, 卷号: 35, 期号: 10, 页码: 9563-9569
作者:  Wang, Yi;  Nie, Fangyuan;  Ouyang, Jian;  Wang, Xiaoyan;  Ma, Xiaofeng
浏览  |  Adobe PDF(780Kb)  |  收藏  |  浏览/下载:454/129  |  提交时间:2014/12/19
Fatty Acid Synthase  Inhibitor  Sea Buckthorn  Procyanidins  Mda-mb-231 Cells  Cell Apoptosis  
Discovery of a New Series of Naphthamides as Potent VEGFR-2 Kinase Inhibitors 期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 5, 期号: 5, 页码: 592-597
作者:  Lv, Yongcong;  Li, Mengyuan;  Liu, Ting;  Tong, Linjiang;  Peng, Ting;  Wei, Lixin;  Ding, Jian;  Xie, Hua;  Duan, Wenhu
浏览  |  Adobe PDF(2015Kb)  |  收藏  |  浏览/下载:466/130  |  提交时间:2014/12/19
Angiogenesis  Huvec  Inhibitor  Naphthamide  Vegfr-2  
Theoretical studies on the interaction of biphenyl inhibitors with Mycobacterium tuberculosis protein tyrosine phosphatase MptpB 期刊论文
JOURNAL OF MOLECULAR MODELING, 2012, 卷号: 18, 期号: 8, 页码: 3847-3856
作者:  Dong, Lihua;  Shi, Junyou;  Liu, Yongjun
浏览  |  Adobe PDF(890Kb)  |  收藏  |  浏览/下载:771/168  |  提交时间:2013/03/15
Tyrosine Phosphatase b  Biphenyl Inhibitor  Interaction  Molecular Docking  Molecular Dynamics Simulation  
Theoretical Studies on the Conformational Change of Adenosine Kinase Induced by Inhibitors 期刊论文
INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY, 2011, 卷号: 111, 期号: 14, 页码: 3980-3990
作者:  Dong, Lihua;  Shi, Junyou;  Wang, Jinhu;  Liu, Yongjun
浏览  |  Adobe PDF(1320Kb)  |  收藏  |  浏览/下载:859/208  |  提交时间:2011/12/13
Adenosine Kinase (Ak)  Inhibitor  Conformational Change  Molecular Dynamic (Md)  
Receptor-based QSAR study for a series of 3,3-disubstituted-5-aryl oxindoles and 6-aryl benzimidazol-2-ones derivatives as progesterone receptor inhibitors 期刊论文
SAR AND QSAR IN ENVIRONMENTAL RESEARCH, 2011, 卷号: 22, 期号: 7-8, 页码: 775-799
作者:  Wang, J. H.;  Hou, Q. Q.;  Tang, K.;  Cheng, X. L.;  Dong, L. H.;  Liu, Y. J.;  Liu, C. B.
浏览  |  Adobe PDF(1310Kb)  |  收藏  |  浏览/下载:1244/271  |  提交时间:2011/12/14
Progesterone Receptor  Comparative Molecular Field Analysis (Comfa)  Comparative Molecular Similarity Indices Analysis (Comsia)  Inhibitor  Qsar  
STUDY ON THE INTERACTIONS OF Smac MIMETICS WITH XIAP-BIR3 DOMAIN BY DOCKING AND MOLECULAR DYNAMICS SIMULATIONS 期刊论文
JOURNAL OF THEORETICAL & COMPUTATIONAL CHEMISTRY, 2010, 卷号: 9, 期号: 4, 页码: 797-812
作者:  Ling, Baoping;  Zhang, Rui;  Wang, Zhiguo;  Liu, Yongjun;  Liu, Chengbu
浏览  |  Adobe PDF(1006Kb)  |  收藏  |  浏览/下载:695/147  |  提交时间:2011/12/13
Inhibitor Of Apoptosis Protein (Iap)  Smac Mimetics  Molecular Docking  Molecular Dynamics Simulations  Binding Free Energy