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Robust hybrid enzyme nanoreactor mediated plasmonic sensing strategy for ultrasensitive screening of anti-diabetic drug 期刊论文
BIOSENSORS & BIOELECTRONICS, 2018, 卷号: 99, 页码: 653-659
作者:  Kong, Weiheng;  Wu, Di;  Hu, Na;  Li, Ning;  Dai, Chunji;  Chen, Xuefeng;  Suo, Yourui;  Li, Guoliang;  Wu, Yongning
收藏  |  浏览/下载:267/0  |  提交时间:2017/12/08
Hybrid Enzyme Hierarchical Structure  Alpha-glucosidase  Plasmonic Sensing  Anti-diabetic Drug  
A critical role for very long-chain fatty acid elongases in oleic acid-mediated Saccharomyces cerevisiae cytotoxicity 期刊论文
MICROBIOLOGICAL RESEARCH, 2018, 卷号: 207, 页码: 1-7
作者:  Wang, Qiao;  Du, Xiuxiu;  Ma, Ke;  Shi, Ping;  Liu, Wenbin;  Sun, Jing;  Peng, Min;  Huang, Zhiwei
收藏  |  浏览/下载:186/0  |  提交时间:2018/07/25
Fatty Acids Elongases  Very Long-chain Fatty Acids  Oleic Acid  Lipotoxicity  Oxidative Stress  Membrane Permeability  
A simple and novel colorimetric assay for tyrosinase and inhibitor screening using 3,3 ',5,5 '-tetramethylbenzidine as a chromogenic probe 期刊论文
TALANTA, 2017, 卷号: 175, 页码: 457-462
作者:  Lei, Cuihua;  Zhao, Xian-En;  Sun, Jing;  Yan, Xiaolu;  Gao, Yue;  Gao, Han;  Zhu, Shuyun;  Wang, Hua
收藏  |  浏览/下载:282/0  |  提交时间:2017/12/08
Silver Ion (Ag++)  Tyrosinase  Enzyme Inhibition  Colorimetric Assay  3  3 '  5  5 '-tetramethylbenzidine (Tmb)  
A fluorescence resonance energy transfer (FRET) based "Turn-On" nanofluorescence sensor using a nitrogen-doped carbon dot-hexagonal cobalt oxyhydroxide nanosheet architecture and application to alpha-glucosidase inhibitor screening 期刊论文
BIOSENSORS & BIOELECTRONICS, 2016, 卷号: 79, 页码: 728-735
作者:  Li, Guoliang;  Kong, Weiheng;  Zhao, Mei;  Lu, Shuaimin;  Gong, Peiwei;  Chen, Guang;  Xia, Lian;  Wang, Hua;  You, Jinmao;  Wu, Yongning
收藏  |  浏览/下载:238/0  |  提交时间:2016/07/19
Nitrogen-doped Carbon Dots  Alpha-glucosidase  Enzyme Inhibition  Fluorescence Resonance Energy Transfer  
Novel Diketopiperazine Dihydroorotate Dehydrogenase Inhibitors Purified from Traditional Tibetan Animal Medicine Osteon Myospalacem Baileyi 期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2015, 卷号: 86, 期号: 4, 页码: 626-636
作者:  Jiang, Lei;  Wen, Huaixiu;  Shao, Yun;  Yu, Ruitao;  Liu, Zenggen;  Wang, Shuo;  Wang, Qilan;  Zhao, Xiaohui;  Zhang, Peng;  Tao, Yanduo;  Mei, Lijuan
浏览  |  Adobe PDF(1151Kb)  |  收藏  |  浏览/下载:359/133  |  提交时间:2015/12/17
Cyclic Dipeptides  Dihydroorotate Dehydrogenase Inhibitors  Osteon Myospalacem Baileyi  Tibetan Medicine  Two-dimensional Chromatography  
Cadmium interferes with maintenance of auxin homeostasis in Arabidopsis seedlings 期刊论文
JOURNAL OF PLANT PHYSIOLOGY, 2013, 卷号: 170, 期号: 11, 页码: 965-975
作者:  Hu, Yan Feng;  Zhou, Guoying;  Na, Xiao Fan;  Yang, Lijing;  Nan, Wen Bin;  Liu, Xu;  Zhang, Yong Qiang;  Li, Jiao Long;  Bi, Yu Rong;  Bi, YR (reprint author), Lanzhou Univ, Sch Life Sci, Minist Educ, Key Lab Cell Act & Stress Adaptat, Lanzhou 730000, Gansu, Peoples R China.
Adobe PDF(3113Kb)  |  收藏  |  浏览/下载:657/183  |  提交时间:2014/05/09
Arabidopsis  Auxin Homeostasis  Cadmium  Heavy Metal  Lateral Root  
Theoretical study on the proton shuttle mechanism of saccharopine dehydrogenase 期刊论文
JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2013, 卷号: 44, 页码: 17-25
作者:  Sheng, Xiang;  Gao, Jun;  Liu, Yongjun;  Liu, Chengbu
Adobe PDF(2598Kb)  |  收藏  |  浏览/下载:945/139  |  提交时间:2014/05/09
Saccharopine Dehydrogenase  L-lysine Biosynthesis  Density Functional Theory (Dft) Method  Proton Shuttle  Reaction Mechanism  
Theoretical Studies on the Conformational Change of Adenosine Kinase Induced by Inhibitors 期刊论文
INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY, 2011, 卷号: 111, 期号: 14, 页码: 3980-3990
作者:  Dong, Lihua;  Shi, Junyou;  Wang, Jinhu;  Liu, Yongjun
浏览  |  Adobe PDF(1320Kb)  |  收藏  |  浏览/下载:855/208  |  提交时间:2011/12/13
Adenosine Kinase (Ak)  Inhibitor  Conformational Change  Molecular Dynamic (Md)  
Effects of cloudiness change on net ecosystem exchange, light use efficiency,and water use efficiency in typical ecosystems of China 期刊论文
Agricultural and Forest Meteorology, 2011, 卷号: 151, 页码: 803-816
作者:  Yu GR(于贵瑞)
浏览  |  Adobe PDF(2324Kb)  |  收藏  |  浏览/下载:575/92  |  提交时间:2011/12/14
Fertilization and litter effects on the functional group biomass, species diversity of plants, microbial biomass and enzyme activity of two alpine meadow communities 期刊论文
Plant Soil, 2010, 卷号: 331, 页码: 377-389
作者:  Wang ZT(王长庭);  Long RJ(龙瑞军);  Wang QL(王启兰);  Liu W(刘伟);  Jing ZC(景增春);  Li Zhang
浏览  |  Adobe PDF(368Kb)  |  收藏  |  浏览/下载:807/168  |  提交时间:2011/12/14